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PFC Achieves High Pregnancy Rates While Lowering Risks

Wednesday, August 11th, 2010
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Every year thousands of families are created with the assistance of in-vitro fertilization. Many of those newborns are twins. While some may see this as a double blessing, it is important to understand that there are many potential risks associated with multiple gestation. Statistics show that a higher percentage of twins are born prematurely compared to singleton pregnancies. Premature birth can cause complications resulting in physical impairment, learning disabilities, and even death. In addition to the increased risk to the children born from a multiple pregnancy, there is also an increased risk for the pregnant woman of complications associated with carrying multiples.

Pacific Fertility Center (PFC) has been taking steps to minimize the risk of multiple gestation for several years. “We have worked actively to increase pregnancy rates and decrease the number of multiples,” comments Carolyn Givens, M.D. “Balancing high pregnancy rates with low pregnancy risk improves pregnancy outcomes. Our goal is to achieve this balance and reduce the risk of multiple gestation.”

PFC recently completed the analysis of our Elective Single Embryo Transfer (eSET) program for 2009. The twin rate was significantly lower, and, triplets were eliminated entirely. 79 patients underwent an embryo transfer procedure where they elected to transfer only one embryo created from their own eggs; these 79 transfers resulted in 38 pregnancies, two of which were identical twin pregnancies (the embryo split from one into two) and NO triplets. Compare this statistic to patients choosing to transfer two embryos: 159 patients, with embryos derived from their own eggs, transferred two embryos resulting in 80 pregnancies, of which 31% were non-identical twins and two triplet pregnancies (again from one of the embryos splitting).

Patients that choose eSET have excellent pregnancy rates with a single embryo. eSET embryos are grown for 5 days in the lab to the blastocyst stage, which allows for selection of the healthiest embryos for transfer. The transfer of fewer embryos provides for the healthiest outcomes; eSET produces high pregnancy rates while minimizing the risk of multiple pregnancy. “For many patients, there is no advantage to transferring more than one embryo. It is all about educating our patients. Given this information, these numbers and the potential risks of twin pregnancies, many will choose to transfer only one embryo,” says Carolyn Givens, M.D.

At PFC, careful consideration is given to the number of embryos transferred to each patient. Our goal is to create healthy singleton pregnancies. Utilizing advanced embryo culture techniques, the highest quality embryos can be selected for transfer. Special environmental conditions, advanced culture media, and the delicate handling of gametes and embryos is required; these efforts result in better embryos, with higher implantation and pregnancy rates.

In addition, PFC has developed an outstanding and robust program for freezing embryos not transferred in the fresh cycle. Using a technology called vitrification, we have been able to achieve pregnancy rates with frozen embryos that are very similar to those using fresh embryos. “The outstanding success of our freezing program has allowed us to be confident in transferring just one embryo at a time, which all but eliminates the risk of triplets or higher pregnancy,” says Dr. Joe Conaghan, PFC Lab Director. He adds, “We have been so successful with embryo freezing over the last 3 years that our embryologists are in high demand to provide training across the country and around the world. Our goal is to help our patients overcome infertility and build their family; one healthy baby at a time.”

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6 Responses to “PFC Achieves High Pregnancy Rates While Lowering Risks”

  1. Max Donathan Says:

    Nice article. I have a question – I am 2 weeks pregnant and my friends been saying that eating Sweetcorn could cause abortion. Is it true? Please let me know. I am checking my doctor tomorrow on this anyway… Keep writing more like this. Thanks!

  2. graziela martini Says:

    Olá..prazer, sou de Porto Alegre – RS – BRASIL;
    Vamos lá, no ano de 2.000 quando tinha 19 anos, fiquei grávida, mas como continuava menstruando não desconfiava… Em abril do mesmo ano, acordei com uma bolinha do lado esquerdo da barriga e gritei para minha mãe, logo falando mãe estou com cancêr (foi a primeira coisa que veio em minha cabeça), ela olhou para mim e disse; filha você esta grávida, seus seios estão maiores. Então no dia seguinte marquei 1 ecografia, estava grávida de 14 semanas, fiquei assustada pois não havia me cuidado devidamente como toda gestante. Comecei a fazer o pré natal, 2 semanas depois ( com 16 semanas) tive um sangramento muito grande (parecia uma torneira aberta a toda) fui ao hospital e lá a médica me falou que não havia perdido o bebê. Que alivio pois eu estava tão feliz com esta gravidez, mas ela falou também que tinha acontecido um descolamento de placenta. Tinha que ficar em repouso absoluto. O fiz. Quando cheguei a 26 semanas começaram as contrações, fiu para o hospital e entrei em trabalho de parto, tive um parto prematuro, o bebê nasceu mas não sobreviveu, pois não estav com o pulmão formado.
    Desde então não consigo engravidar já se passarm 10 anos, estou com 28 anos, até parei de tomar a pílula a 8 anos atrás. O que faço me ajude por favor!
    Muito obrigado por ter lido, agradeço do fundo do coração!!!
    Saúde e fiquem com Deus!
    Graziela Martini

  3. Graziela Martini Says:

    Hello. Pleasure, I’m from Porto Alegre – RS – BRAZIL;
    Come on in the year 2000 when she was 19, got pregnant, but as still menstruating did not suspect … In April of that year, I woke up with a ball on the left side of my stomach and I yelled to my mother, I’m just speaking mother had cancer (it was the first thing that came into my head), she looked at me and said, you daughter is pregnant , her breasts are bigger. Then the next day scored an ultrasound was 14 weeks pregnant, I was scared because I did not care due to all pregnant women. I started doing pre natal, two weeks later (16 weeks) had a bleeding too big (like a tap open to all) went to the hospital and the doctor there told me that he had not lost the baby. What a relief because I was so happy with this pregnancy, but she also talked about what had happened a detached placenta. Had to be completely at rest. I did it. When I reached 26 weeks the contractions began, fiu to the hospital and went into labor, I had a premature birth, the baby was born but did not survive because he was not trained with the lung.
    Since then I can not get pregnant already passarm 10 years, I’m 28 years until I stopped taking the pill 8 years ago. What do I do help me please!
    Thank you for reading, thank you from the heart!
    Health and stay with God!
    Graziela Martini

  4. admin Says:

    Max,
    I would recommend that you speak to your ob/gyn, as you are already pregnant. It seems that you may have already done that. Thanks for your question and comment!

    -Molly

  5. admin Says:

    Boa Tarde Graziela,

    Here is some information in Portuguese, which I hope will help you. Please keep in mind that our doctors do not speak Portuguese.

    Obrigado por seu interesse em Pacific Fertility Center. Nós sempre aceitamos novos pacientes.

    Nossos médicos não falam português e nós não temos um em serviço de tradução. Portanto, deverá fornecer o próprio tradutor para todas suas consultas. Há um serviço de tradução com o Language Bank em San Francisco. O número é (415)885-0827.

    Para fazer uma consulta, por favor contata nossos Coordenadores dos Novos Pacientes em 415-834-3095. Oferecemos dois tipos de consultas iniciais, sobre o telefone ou em nosso escritório. A consulta de telefone é uma consulta gratis de meia hora com o médico que revisará com você seus exames médicos e discute o que um curso de tratamento talvez seja para sua situação.

    Antes de qualquer consulta, o médico deve ter as seguintes informações:

    1) Registros médicos relacionados a fertilidade (uma forma de ésta ligada para sua conveniência). Estes incluiriam:

    a) As resultas das provas de FSH e Estradiol pra mulher (isto é um exame de sangue feito no 2o 3o dia de seu período).
    b) Análise de Sêmen pro homem.
    c) Qualquer outros registros médicos de fertilidade, inclusive tratamento prévio ou recomendação de tratamento por um médico prévio.

    2) As formas de História do Paciente. Depois que nós fazemos sua consulta, nós daremos você acessa a nosso sistema eletrônico onde você completará nossas formas de história. Se você quer começar a trabalhar neles agora, por favor sigam a conexão:

    https://connect.pacificfertilitycenter.com/patient/ivflogin.asp e escolha “New Patients- Request New User ID and Password.” Ao completar esta forma nós teremos todas as informações necessárias dar você acessa a nosso sistema eletrônico.

    As provas mencionadas acima de fornecer o médico com algumas informações importantes. O FSH/Estradiol é um indicador bom de sua reserva ovariana, ou qualidade de ovo. A análise de sêmen permite que o médico avalie a qualidade do sêmen. Juntos, eles ajudam o médico a desenvolver um plano de tratamento para sua situação específica. Para uma melhor explicação da prova, por favor revisa a seguinte conexão de nosso site: http://www.pacificfertilitycenter.com/infertility/evaluation.php e http://www.pacificfertilitycenter.com/infertility/age.php. Nosso site http://www.pacificfertilitycenter.com também tem informações úteis.

    Por favor visite nosso site em http://www.pacificfertilitycenter.com para mais informações sobre PFC. Por favor não hesite em chamar Coordenadores dos Pacientes Novos se você tem perguntas e fazer uma consulta inicial. Nós estamos aqui segunda-feira até sexta-feira de 8:30am a 4:30pm e você pode ligar nos em 888-834-3095 ou 415-834-3095.

    Muito Obrigado,

    Jessica

  6. eyaculación precoz Says:

    It is actually the great as well as useful section of info. I am happy that you just discussed this particular useful information around. Make sure you keep all of us up to date such as this. Thanks with regard to discussing.

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Welcome to InfertilityDoctor.com, blog of Pacific Fertility Center. Located in San Francisco, California, PFC is the leading Bay Area infertility clinic specializing in PGD: preimplantation genetic diagnosis, IVF: in vitro fertilization, egg donor programs, embryo freezing, ICSI & IVF as well as other advanced female and male infertility treatment solutions. Our office is conveniently located near the Bay Bridge and is accessible to those traveling from Bay Area communities such as the East Bay (Berkeley, Oakland, and Walnut Creek), North Bay (Marin and Santa Rosa), Peninsula (San Mateo), and South Bay (San Jose). Our office is also less than an hour-and-a-half from Northern California communities such as Sacramento and Stockton.
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